Computational Biology

Bioinformatics Consultation Expertise

We provide expert and end-to-end bioinformatics consultation that enables our clients to quantify and decipher complex biological data effectively.

Our extensive expertise includes pooled and single-cell transcriptomics, secondary structure probing and analysis, human microbiome analysis for therapeutic applications, and structure based metagenomic search. We utilize advanced platforms like Nextflow to ensure scalable, serverless, cloud-agnostic deployment that maximizes research flexibility and efficiency.

Pooled and Single-Cell Transcriptomics Expertise

We offer in-depth expertise in both pooled and single-cell transcriptomics, which allows for detailed gene expression profiling across thousands of individual cells or pooled samples. This capability is essential for exploring cellular heterogeneity and understanding dynamic cellular responses, providing critical insights into disease mechanisms and potential drug targets. Our contributions help in dissecting complex biological systems, propelling advances in personalized medicine and therapeutic development.

Secondary Structure Probing and ncRNA Sequence Analysis

Our proficiency in secondary structure probing employs computational methods to predict and analyze the folding patterns of nucleic acids. This expertise supports the rational design of RNA-based therapeutics and enhances our understanding of RNA’s regulatory roles in various biological processes, offering crucial insights for therapeutic interventions. Additionally, we specialize in secondary structure-based search and clustering of non-coding RNA (ncRNA) sequences. This approach is vital for identifying functional ncRNAs involved in regulatory processes, which are potential targets for RNA therapeutics. By clustering similar structures, we can predict functional relationships and identify novel therapeutic candidates.

Human Microbiome Analysis for Therapeutic Applications

Specializing in human microbiome analysis, we empower our clients to explore microbial communities within the human body. This analysis is critical for the development of microbiome-based therapeutics, aimed at harnessing the potential of microbiota to treat and prevent disease. We provide comprehensive insights into microbial diversity, function, and dynamics, which are pivotal for identifying novel therapeutic targets and developing effective microbiome therapeutics.

Leveraging Nextflow for Scalable, Cloud-Agnostic Deployment

Using Nextflow, we expertly design and manage bioinformatics pipelines that are robust, reproducible, and scalable. Nextflow allows us to orchestrate complex workflows efficiently across multiple computing environments. Our cloud-agnostic approach offers clients the flexibility to deploy these pipelines on any cloud platform, ensuring they can operate within their preferred computational environments without sacrificing power or data security.